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Principles of Nucleotide Activity

  • PHA 6535 Principles of Nucleotide Activity

    Credits: 2


    This course will introduce students to the chemical structure of DNA and RNA; the synthetic processes for DNA and RNA synthesis; biochemical reactions and pathways for nucleotide synthesis; DNA replication, transcription and translation; covalent and reversible interactions of nucleic acids with small molecules and proteins and an overview of techniques for the analysis of nucleic acids.


    Please review our recommended course order.


    Module Topic
    Module 1 DNA and RNA Structure
    Module 2 DNA Packaging, Replication, Repair, and Recombination
    Module 3 RNA Sequence Information
    Module 4 Nucleotide Biosynthesis
    Module 5 The Role of Nucleotides in Protein Synthesis and Protein-Nucleic Acid Interactions
    Module 6 Reversible and Covalent Interactions of Nucleic Acids with Small Molecules
    Module 7 Chemical Synthesis
    Module 8 Techniques Applied to Nucleic Acids

    Required Materials

    Lehninger Principles of Biochemistry 7th Edition
    by David L. Nelson, Michael M. Cox
    Publisher: MacMillan Learning; 7th edition (2017)
    ISBN-13: 978-1464126116
    ISBN-10: 1464126119

    Please note: this is the same text that is required for Metabolic Biochemistry, PHA 6935

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    At a Glance

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